Buy Clomiphene Citrate for Men
Together with the suspension of Cincinnati Reds pitcher Edinson Volquez for performance enhancing drug use as well as a swirl of rumors the agent involved was clomiphene (also called Clomid,) I thought it timely to write about how exactly clomiphene works and how itâs used. From what I read on the internets, there’s an enormous amount of misinformation.
You need to know the method by which the pituitary controls the making of testosterone in the testis to understand clomiphene works. Leydig cells make testosterone . The pituitary releases a hormone called luteinizing hormone (âLHâ) that stimulates the Leydig cells to make testosterone. Testosterone is converted to the female hormone estrogen, (which I also explained in my last post,) and estrogen tells the pituitary to stop making more LH. In regards to hormones work, this kind of negative feedback system is common. Itâs just just like a thermostat and heater. As the room gets warmer, less electricity is sent by the thermostat to the heater. When the room gets colder, more electricity is sent by the thermostat to the heater.
By blocking estrogen in the pituitary clomiphene functions. The pituitary makes more LH, and sees less estrogen. More LH means the Leydig cells in the testis make more testosterone.
As I explained in my last post, giving testosterone to your man does the opposite. The pituitary thinks the testis is making plenty of testosterone, and LH falls. Consequently, the testis stops making testosterone, as well as the high levels of testosterone in the testis fall to the lower level in the blood.
So clomiphene is a way to increase testosterone in the testis as well as the blood in the same time. It preserves function and testis size .
Clomiphene isn’t FDA. For women, the pharmaceutical company that sought approval did it like the majority of of the medications that individuals use to treat male fertility. Clomiphene is now generic, and itâs unlikely that anyone will pony up the hundreds of millions of dollars necessary to get it approved for the male. Thatâs the bad news. The good news is that it means this medication is inexpensive, cheaper than most forms of prescription testosterone. Can clomiphene Be prescribed by a doctor to get a man? Yes. Itâs âoff labelâ, meaning that itâs not FDA approved for use in men.
Clomiphene is well tolerated by men. Within my experience, most patients donât feel anything as their testosterone rises. The ones that do feel an increase in sex drive, energy, and muscle mass, especially when they work out. Very rarely Iâve had patients report they feel too aggressive, or too angry. Very very rarely (twice in the last 20 years) Iâve had patients report visual changes. Thatâs worrisome, as the pituitary is close to the optic nerve in the brain, and visual changes suggests the pituitary may be changing in size. Since the skull is a closed space, itâs alarming if anything in the brain changes in size. In the last twenty years, Iâve also had two patients who had breast enlargement (called âgynecomastiaâ) while using clomiphene. Needless to say, for some of those side effects that were problematic, the clomiphene is discontinued.
So thatâs the story with clomiphene. It might be used in the male, either for low or fertility testosterone levels. Itâs an off label prescription drug. It is well tolerated, and works.